研究代表者を二重下線で研究分担者を下線で示してあります。
2023
和文誌「顕微鏡」に本領域の特集が掲載されました
特集：新時代の生命科学・医学におけるクロススケールバイオロジーと人のネットワークの必要性
吉川雅英領域代表（東京大学）が日本顕微鏡学会学会賞（瀬藤賞）を受賞しました
第68回 令和5年度 学会賞（瀬藤賞）「クライオ電子顕微鏡を用いた細胞骨格・モーター分子の機能構造連関の解明」
佐藤繭子先生（理化学研究所）が日本顕微鏡学会奨励賞を受賞しました
第24回 令和5年度 奨励賞「高圧凍結技法の生物試料への応用」
吉川班・小田班の共同研究成果
Yanagisawa H, Kita Y, Oda T, Kikkawa M
Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane
Commun. Biol. (2023) DOI: 10.1038/s42003-023-05393-x
吉川班の研究成果
Kikkawa M
A quest to unravel the role of the stalk and microtubule-binding domain of axonemal dyneins
FEBS Lett. (2023) DOI: 10.1002/1873-3468.14707
小田班・吉川班の共同研究成果
Kubo T, Tani Y, Yanagisawa HA, Kikkawa M, Oda T
α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly
J. Cell Sci. (2023) DOI: 10.1242/jcs.261070
吉川班の研究成果
Yamaguchi H, Morikawa M, Kikkawa M
Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates
eLife (2023) DOI: 10.7554/eLife.84860
吉川班の研究成果
Ito C, Makino T, Mutoh T, Kikkawa M, Toshimori K
The association of ODF4 with AK1 and AK2 in mice is essential for fertility through its contribution to flagellar shape
Sci. Rep. (2023) DOI: 10.1038/s41598-023-28177-z
吉川班の研究成果
Takeda H, Busto JV, Lindau C, Tsutsumi A, Tomii K, Imai K, Yamamori Y, Hirokawa T, Motono C, Ganesan I, Wenz LS, Becker T, Kikkawa M, Pfanner N, Wiedemann N, Endo T
A multipoint guidance mechanism for β-barrel folding on the SAM complex
Nat. Struct. Mol. Biol. (2023) DOI: 10.1038/s41594-022-00897-2
杉田班の研究成果
Ugarte La Torre D, Takada S, Sugita Y
Extension of the iSoLF implicit-solvent coarse-grained model for multicomponent lipid bilayers
J. Chem. Phys. (2023) DOI: 10.1063/5.0160417
杉田班の研究成果
Jung J, Kobayashi C, Sugita Y
Acceleration of generalized replica exchange with solute tempering simulations of large biological systems on massively parallel supercomputer
J. Comput. Chem. (2023) DOI: 10.1002/jcc.27124
杉田班の研究成果
Tan C, Niitsu A, Sugita Y
Highly charged proteins and their repulsive interactions antagonize biomolecular condensation
JACS Au (2023) DOI: 10.1021/jacsau.2c00646
福間班の研究成果
Miyazawa K, Penedo M, Furusho H, Ichikawa T, Alam MS, Miyata K, Nakamura C, Fukuma T
Nanoendoscopy-AFM for visualizing intracellular nanostructures of living cells
Microsc. Microanal. (2023) DOI: 10.1093/micmic/ozad067.387
福間班の研究成果
Ichikawa T, Alam MS, Penedo M, Matsumoto K, Fujita S, Miyazawa K, Furusho H, Miyata K, Nakamura C, Fukuma T
Protocol for live imaging of intracellular nanoscale structures using atomic force microscopy with nanoneedle probes
STAR Protoc. (2023) DOI: 10.1016/j.xpro.2023.102468
福間班の研究成果
Biyani R, Hirata K, Oqmhula K, Yurtsever A, Hongo K, Maezono R, Takagi M, Fukuma T, Biyani M
Biophysical properties of the fibril structure of the toxic conformer of amyloid-β42: characterization by atomic force microscopy in liquid and molecular docking
ACS Appl. Mater. Interfaces. (2023) DOI: 10.1021/acsami.3c06460
福間班の研究成果
Tsujioka M, Miyazawa K, Ohmuraya M, Nibe Y, Shirokawa T, Hayasaka H, Mizushima T, Fukuma T, Shimizu S
Identification of a novel type of focal adhesion remodelling via FAK/FRNK replacement, and its contribution to cancer progression
Cell Death Dis. (2023) DOI: 10.1038/s41419-023-05774-4
水上班の研究成果
Matsui Y, Kowada T, Ding Y, Sahoo PR, Kikuchi K, Mizukami S
Long-term imaging of intranuclear Mg2+ dynamics during mitosis using a localized fluorescent probe
Chem. Commun. (2023) DOI: 10.1039/d2cc05930d
仁田班の研究成果
Yamada S, Ko T, Ito M, Sassa T, Nomura S, Okuma H, Sato M, Imasaki T, Kikkawa S, Zhang B, Yamada T, Seki Y, Fujita K, Katoh M, Kubota M, Hatsuse S, Katagiri M, Hayashi H, Hamano M, Takeda N, Morita H, Takada S, Toyoda M, Uchiyama M, Ikeuchi M, Toyooka K, Umezawa A, Yamanishi Y, Nitta R, Aburatani H, Komuro I
TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy
Sci. Adv. (2023) DOI: 10.1126/sciadv.ade7047
倉永班の研究成果
Aida A, Yuswan K, Kawai Y, Hasegawa K, Nakajima YI, Kuranaga E
Drosophila innate immunity suppresses the survival of xenografted mammalian tumor cells
Sci. Rep. (2023) DOI: 10.1038/s41598-023-38489-9
倉永班の研究成果
Fujita H, Kaneshiro J, Takeda M, Sasaki K, Yamamoto R, Umetsu D, Kuranaga E, Higo S, Kondo T, Asano Y, Sakata Y, Miyagawa S, Watanabe TM
Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation
Life Sci. Alliance (2023) DOI: 10.26508/lsa.202302070
倉永班の研究成果
Uechi H, Kuranaga E
Underlying mechanisms that ensure actomyosin-mediated directional remodeling of cell-cell contacts for multicellular movement: Tricellular junctions and negative feedback as new aspects underlying actomyosin-mediated directional epithelial morphogenesis: Tricellular junctions and negative feedback as new aspects underlying actomyosin-mediated directional epithelial morphogenesis
Bioessays (2023) DOI: 10.1002/bies.202200211
倉永班の研究成果
Nagai H, Nagai LAE, Tasaki S, Nakato R, Umetsu D, Kuranaga E, Miura M, Nakajima Y
Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth in Drosophila
Dev. Cell (2023) DOI: 10.1016/j.devcel.2023.08.022
田中班の研究成果
Endo R, Chen YK, Burke J, Takashima N, Suryawanshi N, Hui KK, Miyazaki T, Tanaka M
Dysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3
Proc. Natl. Acad. Sci. U.S.A. (2023) DOI: 10.1073/pnas.2211522120
山本班の研究成果
Yamamoto H, Matsui T
Molecular mechanisms of macroautophagy, microautophagy, and chaperone-mediated autophagy
J. Nippon Med. Sch. (2023) DOI: 10.1272/jnms.JNMS.2024_91-102
藤芳班の研究成果
Otomo K, Dewa T, Matsushita M, Fujiyoshi S
Cryogenic single-molecule fluorescence detection of the mid-Infrared response of an intrinsic pigment in a light-harvesting complex
J. Phys. Chem. B (2023) DOI: 10.1021/acs.jpcb.3c00284
WONG班の研究成果
Ikliptikawati DK, Hirai N, Makiyama K, Sabit H, Kinoshita M, Matsumoto K, Lim K, Meguro-Horike M, Horike SI, Hazawa M, Nakada M, Wong RW
Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
Cell. Rep. (2023) DOI: 10.1016/j.celrep.2023.112882
村越班の研究成果
Tsujioka S, Sumino A, Nagasawa Y, Sumikama T, Flechsig H, Puppulin L, Tomita T, Baba Y, Kakuta T, Ogoshi T, Umeda K, Kodera N, Murakoshi H, Shibata M
Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy
Sci. Adv. (2023) DOI: 10.1126/sciadv.adh1069
柊元班の研究成果
Kukimoto-Niino M, Ihara K, Mishima-Tsumagari C, Inoue M, Fukui Y, Yokoyama S, Shirouzu M
Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor
Biochem. Biophys. Res. Commun. (2023) DOI: 10.1016/j.bbrc.2023.02.054
丹羽班の研究成果
Niwa S, Chiba K
Generation of recombinant and chickenized scFv versions of an anti-kinesin monoclonal antibody H2
Cytoskeleton (2023) DOI: 10.1002/cm.21756
小金澤班の研究成果
Yamamura M, Hanamura K, Koganezawa N, Furubayashi S, Shirao T, Kawabe H
Impacts of methotrexate on survival, dendrite development, and synapse formation of cortical neurons
Genes Cells (2023) DOI: 10.1111/gtc.13035
加藤班の研究成果
Tasaki K, Zhou Z, Ishida Y, Katoh Y, Nakayama K
Compound heterozygous IFT81 variations in a skeletal ciliopathy patient cause Bardet-Biedl syndrome-like ciliary defects
Hum. Mol. Genet. (2023) DOI: 10.1093/hmg/ddad112
加藤班の研究成果
Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K
Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex
Biol. Open (2023) DOI: 10.1242/bio.059976
稲葉班・吉川班の共同研究成果
Han BB, Watanabe S, Nomura N, Liu K, Uemura T, Inoue M, Tsutsumi A, Fujita H, Kinoshita K, Kato Y, Iwata S, Kikkawa M, Inaba K
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
Nat. Commun. (2023) DOI: 10.1038/s41467-023-40521-5
水上班の研究成果
Fujiwara TK, Takeuchi S, Kalay Z, Nagai Y, Tsunoyama TA, Kalkbrenner T, Iwasawa K, Ritchie KP, Suzuki KGN, Kusumi A
Development of ultrafast camera-based single fluorescent-molecule imaging for cell biology
J. Cell Biol. (2023) DOI: 10.1083/jcb.202110160
水上班の研究成果
Fujiwara TK, Tsunoyama TA, Takeuchi S, Kalay Z, Nagai Y, Kalkbrenner T, Nemoto YL, Chen LH, Shibata ACE, Iwasawa K, Ritchie KP, Suzuki KGN, Kusumi A
Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics
J. Cell Biol. (2023) DOI: 10.1083/jcb.202110162
稲葉班・水上班の共同研究成果
Amagai Y, Yamada M, Kowada T, Watanabe T, Du Y, Liu R, Naramoto S, Watanabe S, Kyozuka J, Anelli T, Tempio T, Sitia R, Mizukami S, Inaba K
Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
Nat. Commun. (2023) DOI: 10.1038/s41467-023-38397-6
稲葉班・吉川班の共同研究成果
Chen Z, Watanabe S, Hashida H, Inoue M, Daigaku Y, Kikkawa M, Inaba K
Cryo-EM structures of human SPCA1a reveal the mechanism of Ca2+/Mn2+ transport into the Golgi apparatus
Science Advances (2023) DOI: 10.1126/sciadv.add9742
加藤班の研究成果
Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT
J. Cell Sci. (2023) DOI: 10.1242/jcs.260462
杉田班の研究成果
Niitsu A, Sugita Y
Towards de novo design of transmembrane α-helical assemblies using structural modelling and molecular dynamics simulation
Phys. Chem. Chem. Phys. (2023) DOI: 10.1039/d2cp03972a
水上班・杉田班の共同研究成果
Sarkar HS, Mashita T, Kowada T, Hamaguchi S, Sato T, Kasahara K, Matubayasi N, Matsui T, Mizukami S
Arylazopyrazole-based photoswitchable inhibitors selective for Escherichia coli dihydrofolate reductase
ACS Chem. Biol. (2023) DOI: 10.1021/acschembio.2c00749
吉川班の研究成果
Eisenstein F, Yanagisawa H, Kashihara H, Kikkawa M, Tsukita S, Danev R
Parallel cryo electron tomography on in situ lamellae
Nat. Methods (2023) DOI: 10.1038/s41592-022-01690-1
仁田班の研究成果
Toyooka K, Goto Y, Hashimoto K, Wakazaki M, Sato M, Hirai MY
Endoplasmic reticulum bodies in the lateral root cap are involved in the direct transport of beta-glucosidase to vacuoles
Plant Cell Physiol. (2023) DOI: 10.1093/pcp/pcac177
山本班の研究成果
Yamamoto H, Zhang S, Mizushima N
Autophagy genes in biology and disease
Nat. Rev. Genet. (2023) DOI: 10.1038/s41576-022-00562-w
WONG班の研究成果
Lim K, Nishide G, Sajidah ES, Yamano T, Qiu Y, Yoshida T, Kobayashi A, Hazawa M, Ando T, Hanayama R, Wong RW
Nanoscopic assessment of anti-SARS-CoV-2 spike neutralizing antibody using high-speed AFM
Nano Lett. (2023) DOI: 10.1021/acs.nanolett.2c04270
丹羽班の研究成果
Chiba K, Kita T, Anazawa Y, Niwa S
Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder
J. Cell Sci. (2023) DOI: 10.1242/jcs.260742
2022
稲葉班・杉田班・吉川班の共同研究成果
Zhang Y, Kobayashi C, Cai X, Watanabe S, Tsutsumi A, Kikkawa M, Sugita Y, Inaba K
Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle
Cell Rep. (2022) DOI: 10.1016/j.celrep.2022.111760
杉田班の研究成果
Okita K, Kasahara K, Matubayasi N
Diffusion theory of molecular liquids in the energy representation and application to solvation dynamics
J. Chem. Phys. (2022) DOI: 10.1063/5.0125432
杉田班の研究成果
Matsunaga Y, Kamiya M, Oshima H, Jung J, Ito S, Sugita Y
Use of multistate Bennett acceptance ratio method for free-energy calculations from enhanced sampling and free-energy perturbation
Biophys. Rev. (2022) DOI: 10.1007/s12551-022-01030-9
児嶋班の研究成果
Taoka K-I, Kawahara I, Shinya S, Harada K-I, Yamashita E, Shimatani Z, Furuita K, Muranaka T, Oyama T, Terada R, Nakagawa A, Fujiwara T, Tsuji H, Kojima C
Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening
Plant J. (2022) DOI: 10.1111/tpj.16008
村越班の研究成果
Murakoshi H, Ueda HH, Goto R, Hamada K, Nagasawa Y, Fuji T
In vivo three- and four-photon fluorescence microscopy using a 1.8 µm femtosecond fiber laser system
Biomed. Opt. Express (2022) DOI: 10.1364/BOE.477322
杉田班の研究成果
Dokainish HM, Sugita Y
Structural effects of spike protein D614G mutation in SARS-CoV-2
Biophys. J. (2022) DOI: 10.1016/j.bpj.2022.11.025
増田班の研究成果
Mori A, Masuda T, Ito S, Ohtsuki S
Human hepatic transporter signature peptides for quantitative targeted absolute proteomics: selection, digestion efficiency, and peptide stability
Pharm. Res. (2022) DOI: 10.1007/s11095-022-03387-8
WONG班の研究成果
Sajidah ES, Lim K, Yamano T, Nishide G, Qiu Y, Yoshida T, Wang H, Kobayashi A, Hazawa M, Dewi FRP, Hanayama R, Ando T, Wong RW
Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM
J. Extracell. Vesicles (2022) DOI: 10.1002/jev2.12275
福間班の研究成果
Hayakawa Y, Takaine M, Ngo KX, Imai T, Yamada MD, Behjat AB, Umeda K, Hirose K, Yurtsever A, Kodera N, Tokuraku K, Numata O, Fukuma T, Ando T, Nakano K, Uyeda TQ
Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II
Life Sci. Alliance (2022) DOI: 10.26508/lsa.202201469
福間班の研究成果
Yurtsever A, Wang P-X, Priante F, Morais Jaques Y, Miyazawa K, MacLachlan MJ, Foster AS, Fukuma T
Molecular insights on the crystalline cellulose-water interfaces via three-dimensional atomic force microscopy
Sci. Adv. (2022) DOI: 10.1126/sciadv.abq0160
水上班の研究成果
Yamamoto T, Yasuda S, Kasai RS, Nakano R, Hikiri S, Sugaya K, Hayashi T, Ogasawara S, Shiroishi M, Fujiwara T, Kinoshita M, Murata T
A methodology for creating mutants of G-protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering
Protein Sci. (2022) DOI: 10.1002/pro.4425
山本班の研究成果
Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J. Cell Biol. (2022) DOI: 10.1083/jcb.202203102
児嶋班の研究成果
Furuita K, Inomata K, Sugiki T, Kobayashi N, Fujiwara T, Kojima C
1H, 13C, and 15N resonance assignments of human glutathione peroxidase 4
Biomol. NMR Assign. (2022) DOI: 10.1007/s12104-022-10090-7
杉田班の研究成果
Matsubara D, Kasahara K, Dokainish HM, Oshima H, Sugita Y
Modified protein-water interactions in CHARMM36m for thermodynamics and kinetics of proteins in dilute and crowded solutions
Molecules (2022) DOI: 10.3390/molecules27175726
福間班の研究成果
Yurtsever A, Wang P-X, Priante F, Morais Jaques Y, Miyata K, MacLachlan MJ, Foster AS, Fukuma T
Probing the structural details of chitin nanocrystal-water interfaces by three-dimensional atomic force microscopy
Small Methods (2022) DOI: 10.1002/smtd.202200320
仁田班の研究成果
Yamada H, Abe T, Nagaoka H, Takashima E, Nitta R, Yamamoto M, Takei K
Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation
Front. Cell. Infect. Microbiol. (2022) DOI: 10.3389/fcimb.2022.992198
仁田班・丹羽班の共同研究成果
Taguchi S, Nakano J, Imasaki T, Kita T, Saijo-Hamano Y, Sakai N, Shigematsu H, Okuma H, Shimizu T, Nitta E, Kikkawa A, Mizobuchi S, Niwa S, Nitta R
Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex
eLife (2022) DOI: 10.7554/eLife.77877
倉永班の研究成果
Masuda-Ozawa T, Fujita S, Nakamura R, Watanabe H, Kuranaga E, Nakajima Y-I
siRNA-mediated gene knockdown via electroporation in hydrozoan jellyfish embryos
Sci. Rep. (2022) DOI: 10.1038/s41598-022-20476-1
山本班の研究成果
Yim WW-Y, Yamamoto H, Mizushima N
A HaloTag-based reporter processing assay to monitor autophagic flux
Autophagy (2022) DOI: 10.1080/15548627.2022.2123638
杉田班の研究成果
Oide M, Sugita Y
Protein folding intermediates on the dimensionality reduced landscape with UMAP and native contact likelihood
J. Chem. Phys. (2022) DOI: 10.1063/5.0099094
山本班の研究成果
Yim WW-Y, Yamamoto H, Mizushima N
A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag
eLife (2022) DOI: 10.7554/eLife.78923
杉田班の研究成果
Tanaka S, Yamamoto N, Kasahara K, Ishii Y, Matubayasi N
Crystal growth of urea and its modulation by additives as analyzed by all-atom MD simulation and solution theory
J. Phys. Chem. B (2022) DOI: 10.1021/acs.jpcb.2c01764
杉田班の研究成果
Nakatani K, Teshigawara S, Tanahashi Y, Kasahara K, Higashi M, Sato H
Solvation in nitration of benzene and the valence electronic structure of the Wheland intermediate
Phys. Chem. Chem. Phys. (2022) DOI: 10.1039/d2cp01699k
福間班の研究成果
Ngo KX, Nguyen PDN, Furusho H, Miyata M, Shimonaka T, Chau NNB, Vinh NP, Nghia NA, Mohammed TO, Ichikawa T, Kodera N, Konno H, Fukuma T, Quoc NB
Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity
Phytopathology (2022) DOI: 10.1094/PHYTO-09-21-0397-R
水上班の研究成果
Hirano M, Ando R, Shimozono S, Sugiyama M, Takeda N, Kurokawa H, Deguchi R, Endo K, Haga K, Takai-Todaka R, Inaura S, Matsumura Y, Hama H, Okada Y, Fujiwara T, Morimoto T, Katayama K, Miyawaki A
A highly photostable and bright green fluorescent protein
Nat. Biotechnol. (2022) DOI: 10.1038/s41587-022-01278-2
児嶋班の研究成果
Shinya S, Katahira R, Furuita K, Sugiki T, Lee Y-H, Hattori Y, Takeshita K, Nakagawa A, Kokago A, Akagi K-I, Oouchi M, Hayashi F, Kigawa T, Takimoto-Kamimura M, Fujiwara T, Kojima C
19F chemical library and 19F-NMR for a weakly bound complex structure
RSC Med. Chem. (2022) DOI: 10.1039/d2md00170e
児嶋班の研究成果
Harada K-I, Furuita K, Yamashita E, Taoka K-I, Tsuji H, Fujiwara T, Nakagawa A, Kojima C
Crystal structure of potato 14-3-3 protein St14f revealed the importance of helix I in StFDL1 recognition
Sci. Rep. (2022) DOI: 10.1038/s41598-022-15505-y
福間班の研究成果
Sumikama T, Federici Canova F, Gao DZ, Penedo M, Miyazawa K, Foster AS, Fukuma T
Computed three-dimensional atomic force microscopy images of biopolymers using the Jarzynski equality
J. Phys. Chem. Lett. (2022) DOI: 10.1021/acs.jpclett.2c01093
倉永班の研究成果
Uechi H, Fukushima K, Shirasawa R, Sekine S, Kuranaga E
Inhibition of negative feedback for persistent epithelial cell-cell junction contraction by p21-activated kinase 3
Nat. Commun. (2022) DOI: 10.1038/s41467-022-31252-0
小田の研究成果
Oda T, Yanagisawa H, Shinmori H, Ogawa Y, Kawamura T
Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation
eLife (2022) DOI: 10.7554/eLife.79990
杉田班の研究成果
Ito S, Yagi K, Sugita Y
Computational analysis on the allostery of tryptophan synthase: relationship between α/β-ligand binding and distal domain closure
J. Phys. Chem. B (2022) DOI: 10.1021/acs.jpcb.2c01556
福間班の研究成果
Ichikawa T, Wang D, Miyazawa K, Miyata K, Oshima M, Fukuma T
Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins
Commun. Biol. (2022) DOI: 10.1038/s42003-022-03437-2
水上班の研究成果
Novianti I, Kowada T, Mizukami S
Clip to Click: controlling inverse electron-demand Diels-Alder reactions with macrocyclic tetrazines
Org. Lett. (2022) DOI: 10.1021/acs.orglett.2c01010
杉田班の研究成果
Shinobu A, Re S, Sugita Y
Practical protocols for efficient sampling of kinase-inhibitor binding pathways using two-dimensional replica-exchange molecular dynamics
Front. Mol. Biosci. (2022) DOI: 10.3389/fmolb.2022.878830
杉田班の研究成果
Heo L, Sugita Y, Feig M
Protein assembly and crowding simulations
Curr. Opin. Struct. Biol. (2022) DOI: 10.1016/j.sbi.2022.102340
杉田班の研究成果
Tan C, Jung J, Kobayashi C, Torre DUL, Takada S, Sugita Y
Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations
PLoS Comput. Biol. (2022) DOI: 10.1371/journal.pcbi.1009578
杉田班の研究成果
Dokainish HM, Re S, Mori T, Kobayashi C, Jung J, Sugita Y
The inherent flexibility of receptor binding domains in SARS-CoV-2 spike protein
eLife (2022) DOI: 10.7554/eLife.75720
水上班・稲葉班の共同研究成果
Liu R, Kowada T, Du Y, Amagai Y, Matsui T, Inaba K, Mizukami S
Organelle-level labile Zn2+ mapping based on targetable fluorescent sensors
ACS Sens. (2022) DOI: 10.1021/acssensors.1c02153
田中班の研究成果
Nakagawa Y, Shen HC-H, Komi Y, Sugiyama S, Kurinomaru T, Tomabechi Y, Krayukhina E, Okamoto K, Yokoyama T, Shirouzu M, Uchiyama S, Inaba M, Niwa T, Sako Y, Taguchi H, Tanaka M
Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system
Nat. Chem. Biol. (2022) DOI: 10.1038/s41589-021-00951-y
吉川班の研究成果
Kikkawa M, Yanagisawa H
Identifying proteins in the cell by tagging techniques for cryo-electron microscopy
Microscopy (2022) DOI: 10.1093/jmicro/dfab059
田中班の研究成果
Hui KK, Endo R, Sawa A, Tanaka M
A perspective on the potential involvement of impaired proteostasis in neuropsychiatric disorders
Biol. Psychiatry (2022) DOI: 10.1016/j.biopsych.2021.09.001
丹羽班の研究成果
Higashida M, Niwa S
Dynein intermediate chains DYCI-1 and WDR-60 have specific functions in Caenorhabditis elegans
Genes Cells (2022) DOI: 10.1111/gtc.12996
仁田班・丹羽班の共同研究成果
Imasaki T, Kikkawa S, Niwa S, Saijo-Hamano Y, Shigematsu H, Aoyama K, Mitsuoka K, Shimizu T, Aoki M, Sakamoto A, Tomabechi Y, Sakai N, Shirouzu M, Taguchi S, Yamagishi Y, Setsu T, Sakihama Y, Nitta E, Takeichi M, Nitta R
CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation
eLife (2022) DOI: 10.7554/eLife.77365
2021
福間班の研究成果
Penedo M, Miyazawa K, Okano N, Furusho H, Ichikawa T, Alam MS, Miyata K, Nakamura C, Fukuma T
Visualizing intracellular nanostructures of living cells by nanoendoscopy-AFM
Sci. Adv. (2021) DOI: 10.1126/sciadv.abj4990
水上班の研究成果
Barabás K, Kobolák J, Godó S, Kovács T, Ernszt D, Kecskés M, Varga C, Jánosi TZ, Fujiwara T, Kusumi A, Téglási A, Dinnyés A, Ábrahám IM
Live-cell imaging of single Neurotrophin receptor molecules on human neurons in Alzheimer’s disease
Int. J. Mol. Sci. (2021) DOI: 10.3390/ijms222413260
吉川班の研究成果
Danev R, Yanagisawa H, Kikkawa M
Cryo-EM performance testing of hardware and data acquisition strategies
Microscopy (2021) DOI: 10.1093/jmicro/dfab016
杉田班の研究成果
Kasahara K, Masayama R, Okita K, Matubayasi N
Atomistic description of molecular binding processes based on returning probability theory
J. Chem. Phys. (2021) DOI: 10.1063/5.0070308
福間班の研究成果
Puppulin L, Kanayama D, Terasaka N, Sakai K, Kodera N, Umeda K, Sumino A, Marchesi A, Weilin W, Tanaka H, Fukuma T, Suga H, Matsumoto K, Shibata M
Macrocyclic peptide-conjugated tip for fast and selective molecular recognition imaging by high-speed atomic force microscopy
ACS Appl. Mater. Interfaces (2021) DOI: 10.1021/acsami.1c17708
福間班の研究成果
Yurtsever A, Das S, Nishimura T, Rodríguez R, Hirose D, Miyata K, Sumino A, Fukuma T, Maeda K
Visualisation of helical structures of poly(diphenylacetylene)s bearing chiral amide pendants by atomic force microscopy
Chem. Commun. (2021) DOI: 10.1039/d1cc05341h
仁田班の研究成果
Saijo-Hamano Y, Sherif AA, Pradipta A, Sasai M, Sakai N, Sakihama Y, Yamamoto M, Standley DM, Nitta R
Structural basis of membrane recognition of Toxoplasma gondii vacuole by Irgb6
Life Sci. Alliance (2021) DOI: 10.26508/lsa.202101149
稲葉班・吉川班の共同研究成果
Zhang Y, Watanabe S, Tsutsumi A, Kadokura H, Kikkawa M, Inaba K
Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca2+-ATPase SERCA2b
EMBO J. (2021) DOI: 10.15252/embj.2021108482